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May 1983

Experimental Gypsy Moth (Lymantria dispar) Ophthalmia Nodosa

Author Affiliations

From the Howe Laboratory of Ophthalmology (Mr Haluska and Dr Albert) and the Harvard Medical School (Drs Puliafito and Albert), Massachusetts Eye and Ear Infirmary, Boston; and Pasaje Mendez Vigo, Barcelona, Spain (Dr Henriquez).

Arch Ophthalmol. 1983;101(5):799-801. doi:10.1001/archopht.1983.01040010799022

• Ophthalmia nodosa is the nodular granulomatous inflammatory response of ocular tissue to caterpillar hairs. We experimentally simulated this condition by surgically implanting gypsy moth hairs in the rabbit cornea. We were not, however, able to produce ophthalmia nodosa solely by placing cilia in the rabbit culde-sac. The experimentally induced inflammation closely resembled human ophthalmia nodosa in both its clinical and histopathologic features.