To the Editor.
—Numerous discussions regarding malignant hyperthermia have appeared in the opthalmologic literature in recent years.1-3 In the May Archives (1982;100:841-843), several authors wrote in concerning a report on malignant hyperthermia by Dodd et al.1 Several controversial points were addressed that I would like to comment on.Malignant hyperthermia does not invariably occur in people susceptible to malignant hyperthermia who undergo anesthesia. In fact, the reverse is true; most people susceptible to malignant hyperthermia can be anesthetized with all the "wrong" drugs without a recognizable malignant hyperthermia syndrome developing.4 It seems that the physiologic state of the person at the time of operation has as much influence as the drugs being used on whether or not he/she will "trigger" the reaction. These drugs, which include many anesthetic agents, can potentiate this condition. Other factors influencing the physiologic state include stress (eg, emotional, traumatic, and so on),
Wingard DW. Malignant Hyperthermia. Arch Ophthalmol. 1983;101(5):820-821. doi:10.1001/archopht.1983.01040010820027