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July 1983

Merkel Cell Tumor of the EyelidA Clinicopathologic Case Report

Author Affiliations

From the Departments of Ophthalmology (Drs Beyer and Dougherty) and Pathology (Drs Goodman and Dickersin), Harvard Medical School; the Massachusetts Eye and Ear Infirmary (Drs Beyer, Goodman, and Dougherty); and Massachusetts General Hospital (Dr Dickersin), Boston.

Arch Ophthalmol. 1983;101(7):1098-1101. doi:10.1001/archopht.1983.01040020100017

• We treated a patient who had clinical and pathological findings of a primary cutaneous tumor of the eyelid with histological and ultrastructural features of a Merkel cell carcinoma. This neoplasm is composed of cells that are thought to be derived from the neural crest and are found normally in the skin. While it may be a low-grade malignant neoplasm, this tumor can grow rapidly and metastasize. Histologically, it can mimic a metastatic undifferentiated small-cell carcinoma from the lung or other primary sites. To our knowledge, this is the first reported case involving an eyelid.