• A small, minimally elevated, nonpigmented choroidal tumor increased in volume 12-fold and grew from the edge of the fovea to the optic disk within 60 days. Histopathology of the enucleated globe demonstrated a mixed spindle and epithelioid cell malignant melanoma with numerous mitotic figures. The calculated doubling time of this tumor was 17 days.
Friberg TR, Fineberg E, McQuaig S. Extremely Rapid Growth of a Primary Choroidal Melanoma. Arch Ophthalmol. 1983;101(9):1375-1377. doi:10.1001/archopht.1983.01040020377006