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November 1983

Monochromatic Fundus Photography of Human Albinos

Author Affiliations

From the Department of Ophthalmic Optics, University of Manchester Institute of Science and Technology, Manchester, England.

Arch Ophthalmol. 1983;101(11):1706-1711. doi:10.1001/archopht.1983.01040020708008

• The clinical diagnosis of albinism can often be uncertain, particularly when one is confronted with blond patients with congenital nystagmus. Monochromatic fundus photography was carried out on 31 patients with congenital nystagmus to examine three retinal features: the macular pigment, foveal vasculature, and the retinal pigment epithelium. All subjects who were later classified as albinos did not exhibit any signs of macular pigmentation. Our results imply that monochromatic fundus photography can be a useful aid in the diagnosis of albinism.