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Article
November 1983

Antibiotics and Corneal Epithelial Wound Healing

Author Affiliations

From the Laboratory of Ophthalmology, Department of Corneal Research, National Institute for Medical Research Unit 86, Hôtel-Dieu Hospital, Paris.

Arch Ophthalmol. 1983;101(11):1775-1778. doi:10.1001/archopht.1983.01040020777023
Abstract

• The healing of a de-epithelialized cornea was measured by serial standardized photography after treatment with different antibiotics. Histological studies were also performed. Low doses of bacitracin (500 units/mL), gentamicin sulfate (3 mg/mL), neomycin (3.5 mg/mL), and chloramphenicol (4 mg/mL) did not retard normal epithelial healing. However, higher doses of bacitracin (10,000 units/mL), gentamicin sulfate (10 mg/mL), and neomycin (8 mg/mL) significantly inhibited reepithelialization.

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