• Congenital anomalous disc changes were associated with acquired macular detachment and peripapillary choroidal neovascularization in two cases. The anomalous disc changes resembled optic nerve pits. In one case, the peripapillary choroidal neovascularization was treated with argon laser photocoagulation, with subsequent reattachment of the macula and considerable improvement in the visual acuity. Although the pathogenesis of macular detachment occurring with optic nerve pits is usually not disclosed by fluorescein angiography, leakage from choroidal neovascularization can occur with this congenital defect and may contribute to the formation of a neurosensory macular detachment. If found, choroidal neovascularization may represent a remedial cause for visual loss in a condition with an otherwise poor prognosis.
Borodic GE, Gragoudas ES, Edward WO, Brockhurst RJ. Peripapillary Subretinal Neovascularization and Serous Macular DetachmentAssociation With Congenital Optic Nerve Pits. Arch Ophthalmol. 1984;102(2):229-231. doi:10.1001/archopht.1984.01040030179021