• Four patients from three consecutive generations of a family with ocular hypotelorism are described. Radiographs document a subnormal distance between the medial orbital walls. To our knowledge, this is the first report of heritable isolated orbital hypotelorism. The pedigree is consistent with an autosomal dominant disorder.
Judisch GF, Kraft SP, Bartley JA, Jacoby CG. Orbital HypotelorismAn Isolated Autosomal Dominant Trait. Arch Ophthalmol. 1984;102(7):995-997. doi:10.1001/archopht.1984.01040030797019