• To investigate the effect of extracapsular lensectomy with posterior capsulotomy, 20,000- and 70,000-dalton dextran was injected into the vitreous of rabbits. The concentration of the 20,000-dalton dextran in the aqueous of aphakic eyes was 14-fold greater than in phakic eyes 3.5 hours after injection of dextran into the vitreous. The aqueous concentration of the 70,000-dalton dextran was four times greater in aphakic eyes after 3.5 hours. The aqueous concentration of a 20,000-dalton dextran in phakic and aphakic eyes became equal between 15.5 and 22.0 hours after injection. Thus, extracapsular lensectomy with posterior capsulotomy increased the rate of movement of a single bolus of both 20,000- and 70,000-dalton dextran preparations from the vitreous to the anterior chamber.
Thompson JT, Glaser BM. Effect of Lensectomy on the Movement of Tracers From Vitreous to Aqueous. Arch Ophthalmol. 1984;102(7):1077-1078. doi:10.1001/archopht.1984.01040030871036