• Itching was cited as a major symptom of their ocular disease by 49 (80%) of the 61 patients with allergic conjunctivitis. Conjunctival scrapings from 51 patients (84%) demonstrated intact eosinophils or eosinophil granules. Eosinophil granules were a useful and recognizable cytologic feature of allergic conjunctivitis even in the absence of intact eosinophils. We believe that a history of itching and the presence of eosinophils or eosinophil granules in conjunctival scrapings are helpful in diagnosing allergic conjunctivitis.
Friedlaender MH, Okumoto M, Kelley J. Diagnosis of Allergic Conjunctivitis. Arch Ophthalmol. 1984;102(8):1198-1199. doi:10.1001/archopht.1984.01040030976029