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Article
September 1984

Essential Blepharospasm and the Meige Syndrome

Arch Ophthalmol. 1984;102(9):1268. doi:10.1001/archopht.1984.01040031028013
Abstract

To the Editor.  —McCord et al1 wrote an informative article in the February Archives. However, they referred to Milroy's disease as oro-facial dystonia. Oro-facial dystonia is usually referred to as the Meige syndrome, after Henri Meige, who described this syndrome in 1910.2 It has also been termed Brueghel's syndrome after the artist Pieter Brueghel, The Elder, who recognized this syndrome in his painting De Gaper.3 The Meige syndrome includes repetitive spasms of the orbicularis muscles and dystonic movements of the lower face, mouth, and lips. The jaw, neck, and soft palate may also be involved. Benign essential blepharospasm is considered to be a forme fruste of this disease.4Milroy's disease refers to chronic hereditary lymphedema, which is an autosomal-dominant disease characterized by chronic edema of the lower extremities. It has also been associated with ptosis, glaucoma, dystrichiasis, incomplete mandibulofacial dystosis, accessory bicuspid teeth, and congenital ectropion.

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