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To the Editor.
—I work in an area of the world where fungus corneal ulcers are common. The results of treatment have been uniformly disappointing. Despite vigorous treatment (including cautery with carbolic acid, silver nitrate, and iodine, and antifungal agents such as amphotericin B, nystatin, and clotrimazole), the ulcer usually progresses, resulting in perforation or the removal of the eye.The ulcer usually begins with an injury from a rice leaf or a stick, followed by treatment with some native medicine made of ground leaves and herbs and applied to the eye. Almost all the cases of fungus ulcers I have encountered occurred in patients of lower socioeconomic backgrounds, whose diet is mainly starchy and lacking in protein.Based on that observation, 15 patients have so far been treated with intravenous (IV) drip infusions of a preparation containing essential amino acids, along with added dietary supplements (eggs, milk, meat, fish,
Joseph M. Fungus Corneal Ulcers. Arch Ophthalmol. 1984;102(11):1583. doi:10.1001/archopht.1984.01040031283002