• Two patients with acute retinal necrosis were treated with vitrectomy, intravitreal infusion of acyclovir, and prophylactic scleral buckling procedures. Both patients have had an uneventful postoperative course and a recovery of visual acuity; follow-up has been at five and 14 months. There has been no sign of toxicity from the intravitreally administered acyclovir by electroretinographic or clinical criteria.
Peyman GA, Goldberg MF, Uninsky E, Tessler H, Pulido J, Hendricks R. Vitrectomy and Intravitreal Antiviral Drug Therapy in Acute Retinal Necrosis SyndromeReport of Two Cases. Arch Ophthalmol. 1984;102(11):1618-1621. doi:10.1001/archopht.1984.01040031308013