• Two eyes were enucleated for angle-closure associated with familial exudative vitreoretinopathy. Characteristic features included total retinal detachment, peripheral retinal vascular proliferation, and a fibrovascular preretinal membrane. Angle-closure glaucoma developed in one case when sudden massive subretinal hemorrhage, associated with abnormal intraretinal vessels, produced anterior displacement of the lens-iris diaphragm; in the second case, angle-closure was associated with the development of rubeosis iridis. Intraretinal inflammatory cells and exudates were also seen in the enucleated eyes.
Boldrey EE, Egbert P, Gass JDM, Friberg T. The Histopathology of Familial Exudative VitreoretinopathyA Report of Two Cases. Arch Ophthalmol. 1985;103(2):238-241. doi:10.1001/archopht.1985.01050020090029