• A localized and asymptomatic metastasis from an untreated choroidal melanoma developed in the thyroid and was incidentally discovered by fine-needle aspiration biopsy. Since metastases from uveal melanoma usually are absent at the time of clinical diagnosis but occur much later in highly predictable sites, the finding of a distant blood-borne metastasis in such an early phase and in the thyroid is very unusual, as illustrated by a review of the literature.
Gherardi G, Scherini P, Ambrosi S. Occult Thyroid Metastasis From Untreated Uveal Melanoma. Arch Ophthalmol. 1985;103(5):689-691. doi:10.1001/archopht.1985.01050050081023