To the Editor.
—It is now well accepted that there is a relationship between intracapsular cataract extraction/lensectomy and postoperative development of rubeosis iridis and neovascular glaucoma in patients undergoing vitrectomy.1 Recently, my associates and I demonstrated the relationship between intracapsular cataract extraction and postoperative development of rubeosis iridis and neovascular glaucoma in diabetic patients, especially in patients with active proliferative diabetic retinopathy.2 The article by Thompson and Glaser3 in the Archives is especially timely and significant because of the current trend toward extracapsular cataract extraction as well as the work being done in Glaser's laboratory on the isolation and identification of a diffusable angiogenesis factor.Their article seemingly shows the importance of the posterior capsule of the lens as a barrier to the diffusion of 20,000- and 70,000-dalton dextran from the vitreous to the anterior chamber, thereby providing experimental data to possibly explain the above clinical findings.
Wand M. Hyaloid Membrane vs Posterior Capsule as a Protective Barrier. Arch Ophthalmol. 1985;103(8):1112. doi:10.1001/archopht.1985.01050080024007