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Article
November 1985

Ocular Lesions Following Methyl Isocyanate Contamination: The Bhopal Experience

Author Affiliations

Bhopal, India

Arch Ophthalmol. 1985;103(11):1627. doi:10.1001/archopht.1985.01050110021002
Abstract

To the Editor.  —During the recent methyl isocyanate leak in Bhopal, India, 232 children were admitted to the Pediatric and Eye Ward of Hamidia Hospital. We report the findings in those children.Exposure lasted one to two hours in 78.4% and greater than two hours in 21.6% of children. All patients complained of severe ocular burning, and other symptoms included lid swelling (94.8%), ocular redness (93.1%), watering (88.7%), pain (75.8%), and photophobia (43.9%). On examination, 215 patients (92.6%) had only mild involvement, with conjunctival vascular engorgement and chemosis. Fourteen patients (6.03% ) had corneal involvement, which ranged from punctate keratopathy to partial or total epithelial denudation. Only three patients (1.28%) had more severe involvement, with stromal haze and iritis. Epithelial healing in all cases was complete within five days, and stromal opacification resolved in an additional two to three days. No secondary infections occurred, and no permanent ocular sequelae ensued. Treatment

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