• Two male patients had corneal endotheliopathy of unknown origin. In both patients it was characterized by continuously progressing bullous keratopathy preceded by a line of keratic precipitates resembling a rejection line. The disease was progressive and did not respond to intensive corticosteroid therapy. No virus could be isolated from the aqueous humor, and the aqueous-antibody titers to herpes simplex, varicella zoster, and measles viruses were below detection level.
Ohashi Y, Kinoshita S, Mano T, Kiritoshi A, Ohji M. Idiopathic Corneal EndotheliopathyA Report of Two Cases. Arch Ophthalmol. 1985;103(11):1666-1668. doi:10.1001/archopht.1985.01050110060025