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March 1986

Second Nonocular Tumors in Survivors of Heritable Retinoblastoma

Author Affiliations

From the Departments of Ophthalmology (Drs Lueder and Judisch) and Preventive Medicine (Mr O'Gorman), University of Iowa Hospitals and Clinics, Iowa City. Dr Lueder is now with St Louis Children's Hospital.

Arch Ophthalmol. 1986;104(3):372-373. doi:10.1001/archopht.1986.01050150072029

• We reviewed the records of 50 patients with heritable retinoblastoma to study the cause of death, if deceased, or the incidence of second nonocular malignant neoplasms. The incidence of second tumors in these patients was 6% at ten years, 14% at 20 years, and 14% at 30 years. These findings are lower than previously reported results. Pinealoma was the probable cause of death in three of the five patients who died of second nonocular tumors.