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August 1986

Embryonal Rhabdomyosarcoma of the ConjunctivaA Clinicopathologic and Immunohistochemical Study

Author Affiliations

From the Departments of Ophthalmology (Dr Cameron), Hennepin County (Minnesota) Medical Center and University of Minnesota School of Medicine, and Laboratory Medicine and Pathology (Dr Wick), University of Minnesota School of Medicine, Minneapolis.

Arch Ophthalmol. 1986;104(8):1203-1204. doi:10.1001/archopht.1986.01050200109062

• Rhabdomyosarcoma of the conjunctiva is a rare lesion, with few previously reported cases. We have observed such a tumor occurring in a 16-year-old girl. The clinical and pathologic entities to be considered in differential diagnosis in such cases are several; in this circumstance, immunohistologic reactivity for desmin and myoglobin (two muscle-related proteins) allows a definitive interpretation of rhabdomyosarcoma to be made. This article documents the clinicopathologic features of the epibulbar rhabdomyosarcoma seen in our patient and discusses the immunocytochemical characteristics of myogenic tumors in general, in the context of ocular neoplasia.