[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.145.232.99. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
February 1987

Thrombin Infusion to Control Bleeding During Vitrectomy for Stage V Retinopathy of Prematurity

Author Affiliations

From the University of Tennessee Medical Center, Memphis.

Arch Ophthalmol. 1987;105(2):203-205. doi:10.1001/archopht.1987.01060020057028
Abstract

• We prospectively studied 36 consecutive premature infants with the diagnosis of retinopathy of prematurity stage V with total traction retinal detachment who underwent lensectomy/vitrectomy and epiretinal membrane delamination. The first 26 patients underwent vitrectomy using thrombin mixed with Balanced Salt Solution Plus at a concentration of 100 U/ mL and the remaining ten patients had pure Balanced Salt Solution Plus used. Intraoperative and postoperative bleeding were monitored. The overall intraoperative bleeding rate was 92% (33/36). Intraoperative bleeding (19% vs 80%) and bleeding at the time of wound closure (4% vs 30%) were both significantly reduced in the thrombin vs no thrombin group.

×