• The histopathologic appearance of five-day-old and 14-day-old krypton red laser-created panretinal photocoagulation lesions in the diabetic human eye is described. The five-day-old lesions were examined near the equator. The 14-day-old lesions were near the temporal arcades and optic disc. Both groups of laser lesions showed a similar degree of damage and occlusion in the lamina choriocapillaris and deeper choroidal vessels. The 14-day-old posterior laser lesions showed outer retinal damage, whereas the five-day-old peripheral lesions showed full-thickness retinal involvement, probably because the peripheral retina is approximately half the thickness of the posterior retina. The five-day-old lesions showed no evidence of repair, whereas the 14-day-old lesions showed an adhesion formed with tight junctions binding Müller's fibers to retinal pigment epithelium.
Johnson RN, Irvine AR, Wood IS. Histopathology of Krypton Red Laser Panretinal PhotocoagulationA Clinicopathologic Correlation. Arch Ophthalmol. 1987;105(2):235-238. doi:10.1001/archopht.1987.01060020089035