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February 1987

Histopathology of Krypton Red Laser Panretinal PhotocoagulationA Clinicopathologic Correlation

Author Affiliations

From the Department of Ophthalmology, University of California at San Francisco. Dr Johnson is currently a Heed Fellow in vitreoretinal diseases at the Bascom Palmer Eye Institute, Miami.

Arch Ophthalmol. 1987;105(2):235-238. doi:10.1001/archopht.1987.01060020089035

• The histopathologic appearance of five-day-old and 14-day-old krypton red laser-created panretinal photocoagulation lesions in the diabetic human eye is described. The five-day-old lesions were examined near the equator. The 14-day-old lesions were near the temporal arcades and optic disc. Both groups of laser lesions showed a similar degree of damage and occlusion in the lamina choriocapillaris and deeper choroidal vessels. The 14-day-old posterior laser lesions showed outer retinal damage, whereas the five-day-old peripheral lesions showed full-thickness retinal involvement, probably because the peripheral retina is approximately half the thickness of the posterior retina. The five-day-old lesions showed no evidence of repair, whereas the 14-day-old lesions showed an adhesion formed with tight junctions binding Müller's fibers to retinal pigment epithelium.