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Article
July 1987

Malignant Fibrous Histiocytoma of the Orbit in a 3-Year-Old Girl

Author Affiliations

Detroit
Royal Oak, Mich

Arch Ophthalmol. 1987;105(7):895-896. doi:10.1001/archopht.1987.01060070031014
Abstract

To the Editor.  —A 3-year-old girl had a malignant fibrous histiocytoma of the left orbit, a rare pediatric tumor. She underwent elective resection of the tumor, allowing preservation of the eye and vision. This was followed by a chemotherapeutic regimen of vincristine sulfate, actinomycin D, and cyclophosphamide. Additionally, orbital radiation totaling 45 Gy (4500 rad) was administered. She had no recurrence over the subsequent 29 months.Fibrous histiocytomas are primitive mesenchymal tumors consisting of varying proportions of histiocytic and fibroblastic cells. These tumors are not uncommon in the elderly. They primarily arise in the extremities, abdomen, and retroperitoneum.1 While several angiomatoid variants of malignant fibrous histiocytoma have been described in pediatric patients, we found only one previously published report describing the characteristic fibrous histiocytoma arising within the orbit of a pediatric patient.2 We now present an additional case.

Report of a Case.  —On Oct 2, 1984, a 3-year-old

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