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July 1987

Choroidal Involvement in Systemic Necrotizing Vasculitis

Author Affiliations

From the Departments of Ophthalmology, University of Washington, Seattle (Drs Kinyoun and Kalina), and Oregon Health Sciences University, Portland (Dr Klein).

Arch Ophthalmol. 1987;105(7):939-942. doi:10.1001/archopht.1987.01060070075032

• Wegener's granulomatosis and lymphomatoid granulomatosis are systemic necrotizing vasculitides of unknown cause. We report similar involvement of the choriocapillaris in these two diseases. A presumed choriocapillaritis caused ischemia and infarction of the choriocapillaris-retinal pigment epithelium-outer neurosensory retina complex. Systemic corticosteroid and immunosuppressive agents were successful in controlling systemic disease and preserving useful vision. At the time of this study, one patient had not had a recurrence for 12 years, and the other patient had been asymptomatic for seven years.