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Article
October 1987

Acanthamoeba Keratitis Masquerading as Corneal Homograft Rejection

Arch Ophthalmol. 1987;105(10):1326-1327. doi:10.1001/archopht.1987.01060100028014
Abstract

To the Editor.  Acanthamoeba keratitis is a rare but increasingly recognized entity. This disease has been associated with trauma, soft contact lens wear, and use of homemade saline solution.1-3 The following case report represents Acanthamoeba keratitis occurring postoperatively in a corneal homograft that was associated with a Saturn-style contact lens.

Report of a Case.  —A 38-year-old man who underwent uncomplicated penetrating keratoplasty in his left eye for keratoconus presented himself to his ophthalmologist 18 months postoperatively complaining of pain in the eye. He had been using a Saturn-style contact lens on a daily basis and used chemical disinfectants. His initial keratitis and corneal epithelial edema progressed over three months to what was believed to be a full-blown corneal homograft rejection with an immune ring. Treatment with topical 1% prednisolone acetate, subconjunctival methylprednisolone, and oral prednisone failed to result in any improvement of the graft reaction and the patient

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