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January 1988

Corneal Damage Following the Use of the Pediculocide A-200 Pyrinate

Arch Ophthalmol. 1988;106(1):16-17. doi:10.1001/archopht.1988.01060130018009

To the Editor.  —The cornea and conjunctiva are sensitive and vulnerable to various chemicals. The extent of the effect depends on the type of chemical and the duration of its contact with the eye tissue.Reinecke and Kinder1 first reported the toxicity of the pediculocide A-200 Pyrinate to the human cornea. A-200 Pyrinate liquid (Norcliff Thayer Inc) is a pediculocide composed of 0.165% pyrethrins, 2% piperonyl butoxide, 5% kerosene (petroleum distillate), and 92.835% (unspecified) inert ingredients. We herein describe the corneal damage that followed the use of A-200 Pyrinate liquid and the method of treatment.Thirty-one children, 18 months to 8 years of age, were referred to our pediatric ophthalmology clinic over a two-year period because of ocular symptoms following the use of pediculocides. Twenty-five children were seen during a campaign period for eradication of pediculosis in school-age children2; 19 of them used A-200 Pyrinate. During the following

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