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January 1988

Acute Leukemia Presenting as a Retinal Pigment Epithelium Detachment

Arch Ophthalmol. 1988;106(1):21-22. doi:10.1001/archopht.1988.01060130023015

To the Editor.  —Leukemic ophthalmopathy can produce hemorrhagic and infiltrative changes of the choroid, retina, optic nerve, or other ocular structures. Serous neuroretinal detachment of the macula and retinal pigment epithelium (RPE) detachment are less common presenting manifestations. We report herein a case of RPE detachment as the unusual presentation of acute leukemia.

Report of a Case.  —A 15-year-old boy presented with sudden blurred vision in his right eye. Corrected visual acuity was 20/ 50 OD and 20/20 OS. Relevant findings were present in the posterior poles, where both maculas appeared elevated, the right greater than the left (Fig 1), with scattered hemorrhages in the fundi. No disc edema was noted. The fluorescein angiogram showed slight macular hypofluorescence in the arteriovenous phase and hyperfluorescent pooling with well-demarcated borders in the late phase in both eyes (Fig 2). Ultrasonography demonstrated no evidence of choroidal thickening.1 Physical examination revealed marked

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