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March 1988

Effects of Topical ALO 2145 (p-Aminoclonidine Hydrochloride, Aplonidine Hydrochloride) on the Acute Intraocular Pressure Rise After Argon Laser Iridotomy-Reply

Author Affiliations

Fort Worth, Tex

Arch Ophthalmol. 1988;106(3):308-309. doi:10.1001/archopht.1988.01060130333005

In Reply.  —We appreciate Dr Fourman's interest in both the acute postoperative IOP elevation following laser iridotomy and our recent articles.1,2 The ability to predict which eyes are at greatest risk of experiencing acute large IOP elevations following iridotomy would be beneficial. We could then prophylactically treat and selectively observe just these susceptible eyes. Dr Fourman's work has not yet been published, so we are unable to review it. We know of no published evidence supporting Dr Fourman's hypothesis that the IOP before iridotomy is related to the postoperative IOP elevation.We have previously reported that one third of eyes experience an IOP elevation greater than 10 mm Hg following both argon and Q-switched neodymium (Nd)-YAG laser iridotomies.3 In this series of eyes, the "IOP elevation did not correlate with preoperative IOP."3 Krupin and coworkers4 also found that the IOP change immediately following argon laser iridotomy

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