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Article
March 1988

Laser Treatment for Choroidal Neovascularization Outside Randomized Clinical Trials

Author Affiliations

From the Texas Retina Associates, Dallas (Dr Jost), and The Retinal Vascular Center, The Wilmer Institute, The Johns Hopkins Medical Institutions, Baltimore (Mss Alexander and Chamberlin and Drs Maguire, Fine, and Murphy).

Arch Ophthalmol. 1988;106(3):357-361. doi:10.1001/archopht.1988.01060130383027
Abstract

• This study was undertaken to determine whether the treatment benefit reported in randomized trials for patients with extrafoveal choroidal neovascular membranes (NVMs) secondary to age-related macular degeneration (AMD) or the ocular histoplasmosis syndrome (OHS) can be duplicated in other clinical settings. The visual results and recurrence rates in treated extrafoveal NVMs of 70 patients with AMD and 21 patients with OHS were similar to those reported by the Macular Photocoagulation Study Group, in which all treated patients received argon blue-green laser photocoagulation after the administration of retrobulbar anesthesia. In this study, 78% (71/ 90) of the patients were treated with krypton laser and only 35% (32/90) had retrobulbar anesthesia. These results suggest, but do not prove, that the wavelength of the laser used or the administration of retrobulbar anesthesia may not be critical variables in determining the success of treatment in patients with extrafoveal NVMs.

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