• Intraocular invasion by neoplastic plasma cells is a rare ophthalmic manifestation of plasma cell dyscrasias. A 67-year-old man who had documented multiple myeloma presented with an infiltration of the iris that simulated a nongranulomatous uveitis. Cytologic examination of the aspirate obtained by anterior chamber paracentesis demonstrated that the infiltrate was composed of neoplastic plasma cells.
Shakin EP, Augsburger JJ, Eagle RC, Ehya H, Shields JA, Fischer D, Koepsell DG. Multiple Myeloma Involving the Iris. Arch Ophthalmol. 1988;106(4):524-526. doi:10.1001/archopht.1988.01060130570039