• We used delayed primary wound closure in three cases of bacterial endophthalmitis to minimize the risk of implant extrusion following evisceration. In a fourth case, the wound was closed primarily, but wound dehiscence and implant extrusion occurred six weeks postoperatively, and reoperation was required. The advantages of delayed primary wound closure following evisceration of the globe for endophthalmitis include rapid removal of the intraocular abscess, continued drainage and mechanical débridement of the infected scleral pouch, and the development of granulation tissue resistant to bacterial growth at the wound margins prior to wound closure. These factors are important in reducing the risk of implant extrusion following evisceration of the globe for endophthalmitis.
Shore JW, Dieckert JP, Levine MR. Delayed Primary Wound ClosureUse to Prevent Implant Extrusion Following Evisceration for Endophthalmitis. Arch Ophthalmol. 1988;106(9):1303-1308. doi:10.1001/archopht.1988.01060140463053