• A patient presented with a large peripapillary choroidal mass as the initial manifestation of widespread, poorly differentiated, large cell lymphoma. The choroidal tumor had clinical and ultrasonographic characteristics of a uveal malignant melanoma. A systemic evaluation and fine-needle aspiration biopsy specimens of the abdomen and choroid established the diagnosis of a lymphoma. On rare occasion, other neoplasms can simulate the diagnostic pattern of uveal melanoma, and fine-needle aspiration biopsy can be crucial in establishing the correct diagnosis.
Fredrick DR, Char DH, Ljung B, Brinton DA. Solitary Intraocular Lymphoma as an Initial Presentation of Widespread Disease. Arch Ophthalmol. 1989;107(3):395-397. doi:10.1001/archopht.1989.01070010405034