To the Editor.
—Choriocarcinoma is a trophoblastic tumor that is usually of placental origin. Metastatic lesions are common, and therefore this diagnosis should be considered in a young woman with metastatic cancer.1 Metastases to the choroid are extremely rare. To our knowledge, this is the first reported case of choroidal metastases of choriocarcinoma responding to systemic chemotherapy.
Report of a Case.
—The patient, a 32-year-old woman, was referred to Moorfields Eye Hospital, London, England, with a 33-day history of blurred vision in her left eye. She denied any previous ocular episodes, medical problems, or constitutional symptoms. She stated that her menses had been irregular for the past 2 months, but denied that she could be pregnant. Her last pregnancy was 4 years earlier.Pinhole acuities were 6/6 OD and 6/12 OS on visual testing. Pupillary responses and ocular movements were normal. The slit-lamp examination findings were normal. Dilated
Barondes MJ, Hamilton AM, Hungerford J, Rustin GJS. Treatment of Choroidal Metastasis From Choriocarcinoma. Arch Ophthalmol. 1989;107(6):796-798. doi:10.1001/archopht.1989.01070010818014