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October 1989

Orbital Amyloidosis Involving the Extraocular Muscles

Author Affiliations

Rochester, Minn

Arch Ophthalmol. 1989;107(10):1428-1429. doi:10.1001/archopht.1989.01070020502019

To the Editor.  —Orbital amyloidosis may be localized to the orbit alone (primary localized orbital amyloidosis) or may be associated with eyelid involvement and systemic amyloidosis.1,2 Primary localized orbital amyloidosis is uncommon, especially if it is isolated to the extraocular muscles.2 This report describes an unusual case of primary localized orbital amyloidosis localized solely to the extraocular muscles, resulting in proptosis and restricted ocular motility. Enlarged extraocular muscles were shown on computed tomography, and massive infiltration by amyloid was documented histopathologically.

Report of a Case.  —A 28-year-old woman was referred to the Mayo Clinic, Rochester, Minn, for evaluation of progressive right proptosis and horizontal diplopia of 1-year's duration. Her medical history was otherwise normal and she specifically denied a history or symptoms of thyroid disease. Visual acuity was 20/20 OU. A 30-diopter right-sided exotropia was present with complete inability to abduct or adduct the eye. Forced ductions of

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