To the Editor.
—The technique of fluorescein angioscopy has been used by ophthalmologists to supplement ophthalmoscopy in the diagnosis of retinal diseases.1,2 The usual technique consists of the intravenous injection of fluorescein sodium following placement of a cobalt blue filter over the illumination source of the indirect ophthalmoscope. The blue light excites the fluorescein, which and this is then visualized in the fundus as a green color. This technique has been used to identify leaking neovascularization, to diagnose cystoid macular edema, to identify nonperfusion of the retina, and to view lesions of the peripheral fundus when fluorescein angiography cannot provide adequate visualization. In patients with opacities in the media (eg, cataract or vitreous hemorrhage) that make fluorescein angiography impossible, fluorescein angioscopy may still allow localization of leaking lesions, such as neovascularization. This is particularly helpful for peripheral retinal lesions, and may allow treatment such as transscleral cryotherapy.The
Jampol LM, Goldberg MF. Improved Method of Fluorescein Angioscopy. Arch Ophthalmol. 1990;108(1):16. doi:10.1001/archopht.1990.01070030018009