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Article
November 1990

Solitary Orbital Involvement With Juvenile Xanthogranuloma

Author Affiliations

From the Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia (Drs Carol and Jerry Shields), and Fairgrounds Medical Center, Allentown, Pa (Dr Buchanon).

Arch Ophthalmol. 1990;108(11):1587-1589. doi:10.1001/archopht.1990.01070130089037
Abstract

• A newborn girl was noted to have a smooth superonasal orbital and preseptal mass at the time of birth. The mass enlarged slightly over 3 months and a biopsy revealed histiocytes and Touton giant cells, compatible with juvenile xanthogranuloma. The infant had no other manifestations of juvenile xanthogranuloma. The mass subsided after systemic corticosteroid therapy was administered. Solitary orbital involvement with juvenile xanthogranuloma is exceedingly rare and most of these patients are found to lack the typical cutaneous lesions. Observation, oral prednisone, or lowdose radiotherapy are recommended forms of treatment.

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