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Article
June 1991

X-Linked Congenital Stationary Night Blindness: Review and Report of a Family With Hyperopia-Reply

Author Affiliations

Chicago, Ill

Arch Ophthalmol. 1991;109(6):766-767. doi:10.1001/archopht.1991.01080060020006
Abstract

In Reply.  —We are grateful for the opportunity to reply to Wright and van Dorp and are pleased to see that our article has generated thought. Our family was one of the families studied in the linkage report by Musarella et al.1 Unfortunately, there was no peak in the lod score of the markers (restriction fragment length polymorphism) between Xp11-Xp21 because there was no recombination in this family. Therefore, our family could not be localized near Xpll or Xp21.As stated in our article,2 the manifestations of CSNB in three of our family members were most consistent with the incomplete type of congenital stationary night blindness, as described by Miyake et al.3 The presentation in our fourth patient was more consistent with the complete type. We believe that this represents phenotypic variation within this family.Wright and van Dorp requested information on our electroretinogram testing conditions for

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