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Article
July 1991

Developments in Ophthalmology, vol 16, Proliferative Vitreoretinopathy, Genetics of Glaucoma

Author Affiliations

Boston, Mass

Arch Ophthalmol. 1991;109(7):930-931. doi:10.1001/archopht.1991.01080070042028

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Abstract

Volume 16 of Developments in Ophthalmology presents three studies. The first two contain new information on the pathogenesis of proliferative vitreoretinopathy. The last discusses the epidemiology of primary congenital glaucoma.

"... new information on the pathogenesis of proliferative vitreoretinopathy... [and] one step closer to an understanding of... 'primary congenital glaucoma.' "

The first study begins with a definition of the problem of proliferative vitreoretinopathy. It summarizes our present solutions, which are primarily surgical. This study carefully documents our present level of understanding concerning the key elements of proliferative vitreoretinopathy, specifically, the cell types and known modulators of these cells. An analogy is developed between the normal woundhealing process and the process of proliferative vitreoretinopathy. The author then focuses on factors that influence the proliferation and migration of retinal pigment epithelial cells, including human vitreous and macrophage products.

The second study is concerned with an immunochemical analysis of per

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