Secondary glaucoma is a common and severe late complication of persistent hyperplastic primary vitreous (PHPV).1 We describe an infant who presented with bilateral PHPV in which glaucoma presented at birth without an apparent secondary cause.
Report of a Case.
—A 4-day-old newborn boy with bilateral cloudy corneas was examined after anesthetization. He was the product of a full-term, uncomplicated pregnancy and weighed 2840 g. The delivery was also uncomplicated. The family history was unremarkable. Both corneas were 10.5 mm in diameter and cloudy. The anterior chambers were deep. The irides had engorged vessels (Figure). Intraocular pressure by pneumatonometry was 51 mm Hg in both eyes. The trabecular meshwork could not be visualized owing to corneal edema. After dilation, bilateral fibrovascular plaques adherent to the posterior lens capsules were discovered (Figure). Patent hyaloid arteries could be traced to the optic nerve heads. The cup-disc ratio was 0.8:1 in both eyes.
Alward WLM, Krasnow MA, Keech RV, Pulido JS, Sutton GL. Persistent Hyperplastic Primary Vitreous With Glaucoma Presenting in Infancy. Arch Ophthalmol. 1991;109(8):1063-1064. doi:10.1001/archopht.1991.01080080021010