Ocular metastases from cutaneous melanoma most commonly involve the uveal tract. Metastases to other structures in the eye are uncommon. We describe a patient with known cutaneous melanoma who was found to have metastatic lesions in the optic disc and vitreous in one eye. Although a vitreous biopsy was performed to establish the diagnosis, comparison of the findings in the present case with those in previously reported cases suggests that the clinical picture of melanoma metastatic to the disc and vitreous is often distinctive enough to be of diagnostic value.
Report of a Case.
—A 36-year-old man complained of floaters and blurred vision in his left eye of 2 weeks' duration. Ten years earlier, he had undergone resection of a cutaneous melanoma from the right side of his neck, and subsequently was treated for pulmonary metastases with radiation, immunotherapy, and a bone marrow transplant.
Pollock SC, Awh CC, Dutton JJ. Cutaneous Melanoma Metastatic to the Optic Disc and Vitreous. Arch Ophthalmol. 1991;109(10):1352-1354. doi:10.1001/archopht.1991.01080100032020