• Using a modified microkeratome, nasally based central corneal flaps were created on six human blind eyes at a depth of 300 μm. The flaps were allowed to heal with a bandage soft contact lens, using neither sutures nor bioadhesives. The optical quality of the corneas was evaluated with biomicroscopic examination, computer-assisted topography, and optical pachometry during a 3-month follow-up period. The maintenance of transparency and lack of distortion of the corneal surface 3 months after surgery support the concept that the flap technique may be useful in laser in situ keratomileusis.
Pallikaris IG, Papatzanaki ME, Siganos DS, Tsilimbaris MK. A Corneal Flap Technique for Laser In Situ KeratomileusisHuman Studies. Arch Ophthalmol. 1991;109(12):1699-1702. doi:10.1001/archopht.1991.01080120083031