• A computerized videokeratography system was used to evaluate diurnal changes in corneal curvature of both untreated and surgically treated eyes of 11 patients who had undergone unilateral radial keratotomy. The mean postoperative interval was 34.5 months. Both corneas operated on and those not operated on steepened on average from morning to evening. For untreated eyes, this diurnal steepening was statistically significant at a distance of 0.5 mm from the corneal apex (mean±SE, 0.36±0.07 diopter) and in the inferotemporal quadrant (0.28±0.08 D); in eyes that had undergone radial keratotomy, steepening was significant at from 1.0 to 3.0 mm from the corneal apex (0.39±0.07 D) and temporal, inferotemporal, inferior, inferonasal, nasal, and superonasal to the corneal apex (0.42±0.08 D). The greatest steepening in the eyes treated with radial keratotomy compared with the untreated eyes occurred at 1.5 to 2.5 mm peripheral to the corneal apex in the inferonasal and nasal octants. Diurnal changes in intraocular pressure, corneal thickness, number of incisions, clear-zone size, postoperative period, and patient sex were not predictive of the magnitude of morning-to-evening change. Furthermore, diurnal changes in corneal curvature of untreated eyes were not predictive of diurnal changes in the fellow eyes after radial keratotomy.
Kwitko S, Gritz DC, Garbus JJ, Gauderman WJ, McDonnell PJ. Diurnal Variation of Corneal Topography After Radial Keratotomy. Arch Ophthalmol. 1992;110(3):351-356. doi:10.1001/archopht.1992.01080150049026