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May 1992

Anterior Ischemic Optic Neuropathy and Intraocular Pressure-Reply

Author Affiliations

Cleveland, Ohio

Arch Ophthalmol. 1992;110(5):597. doi:10.1001/archopht.1992.01080170018005

In Reply.  —We appreciate Dr Katz's careful attention to our article. Although not stated explicitly in our article, all patients fulfilled all inclusion criteria. Our analysis of maximal IOP values was included as an additional means of looking at our data set, while the comparison of mean IOP remained the central emphasis. We agree that such a comparison of maximal IOP likely has a low power and is no substitute for diurnal pressure measurements, as was done in the study by Katz and associates.1 Our study never intended to address the issue of transient peaks of IOP.We included a statement about statistical power so that knowledgeable readers could draw their own conclusions regarding the value of our study. We believe that our sample size was reasonable given the study design. Dr Katz stated that his study found a mean difference in IOP between patients and controls of less

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