Conjunctival edema or chemosis is a common physical finding in many diseases. It has been described with local infections, inflammations, allergies, chemical burns, retrobulbar hemorrhage, trauma, drug use, glandular fever, meningitis, dacrocystitis, styes, insect bites, vaccinal pocks, orbital inflammation or infection, orbital tumors or cysts, blockage of lymphatic veins, angioneurotic edema, Graves' disease, anemia, heart failure, nephrotic conditions, sinusitis, myxedema, premenstrual phase of water retention, carotid-cavernous fistula, thrombosis of cavernous sinus, congenital conjunctival lymphedema, Quincke edema fugax, erysipelas, and lymphogranuloma venereum.1
There is one reported case of chemosis as the initial manifestation of systemic lupus erythematosus (SLE). However, that patient had a nephrotic syndrome secondary to SLE.2 We report a case of chemosis as a presenting sign of SLE in a patient without renal involvement.
Report of a Case.
—A 36-year-old white woman with a 3-month history of chemosis and periorbital edema of both eyes presented at the
Leahey AB, Connor TB, Gottsch JD. Chemosis as a Presenting Sign of Systemic Lupus Erythematosus. Arch Ophthalmol. 1992;110(5):609-610. doi:10.1001/archopht.1992.01080170031011