Malignant lymphoma involving the orbit is uncommon and generally occurs as a low-grade, monoclonal, non-Hodgkin's-type small-cell lymphoma in the sixth and seventh decades. Recently, lymphoma has been reported in association with the acquired immunodeficiency syndrome (AIDS). We report an additional case of human immunodeficiency virus-associated orbital lymphoma with several unusual features.
Report of a Case.
—A 34-year-old male Hispanic intravenous drug user diagnosed with AIDS (human immunodeficiency virus positive, history of multidermatomal herpes zoster, Mycobacterium avium-intracellulare pneumonia, and Candida esophagitis) was examined for a painful soft-tissue mass of the right upper lid, which rapidly progressed over 3 weeks. Physical examination revealed a visual acuity of 6/6 -1 OD and 6/12 - 1 OS. Prominent right periorbital erythema and edema with complete ptosis were associated with a firm, 6-cm palpable mass in the superomedial orbit and brow. Exophthalmometry revealed 8 mm of proptosis in the right eye. Intraocular pressures were 14 mm
Turok DI, Meyer DR. Orbital Lymphoma Associated With Acquired Immunodeficiency Syndrome. Arch Ophthalmol. 1992;110(5):610-611. doi:10.1001/archopht.1992.01080170032012