Don't tell me what you think that I should do. What would you do if this were your patient?," and so go the questions about the use of antimetabolites with filtering surgery. In practice, many difficult and unresolved issues remain. Who should receive these medications and for what conditions? Precisely what therapy should we offer, and when should we initiate or repeat it? With what expectation of improved surgical success can we counsel our patients? What price will our patients pay in terms of an increased complication rate and monetary expense, and for what reward?
See also pp 1049, 1072, and 1150.
Ever since DeWecker1 first produced a fistula between the anterior chamber and the subconjunctival space, variations on this surgical theme have evolved. The modifications have shared the principle of increasing the rate of aqueous egress through a surgically produced channel that bypasses the malfunctioning drainage of the
Parrish RK. Who Should Receive Antimetabolites After Filtering Surgery?. Arch Ophthalmol. 1992;110(8):1069-1071. doi:10.1001/archopht.1992.01080200049022