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May 1993

Effect of Continuous Circular Capsulorhexis and Intraocular Lens Fixation on the Blood-Aqueous Barrier-Reply

Author Affiliations

Osaka, Japan

Arch Ophthalmol. 1993;111(5):581. doi:10.1001/archopht.1993.01090050014004

In Reply.  —We appreciate Dr Brubaker's interest in our article on the effect of continuous circular capsulorhexis and intraocular lens fixation on the blood-aqueous barrier. We agree that the measurement of concentration of aqueous protein would help us to understand the damage to the blood-aqueous barrier in eyes after surgery. Laser flare-cell measurement has been done in our patients 1 to 2 years after surgery. The results will appear in a separate article.There are two reasons why we chose fluorophotometry. First, we would like to compare our results directly with those in the study of Miyake et al,1 in which the result was opposite to ours, namely, fluorophotometry demonstrated a significantly higher permeability in out-of-the-bag fixations than in-the-bag fixations. Second, even if the concentration of a steady-state aqueous protein is independent of the volume of the anterior chamber, aqueous protein, with a molecular weight of more than 60

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