• Follow-up ranging between 6 and 8 years of the survival of a cohort of 473 elderly nondiabetic subjects randomly selected from a small English town showed an age- and sex-adjusted association between nuclear cataract at the time of baseline examination and decreased survival (P=.002). Comparing those with and without nuclear cataract, the adjusted relative hazard for death was 1.52 (95% confidence interval, 1.15 to 1.99). This effect remained virtually unchanged when also adjusted for whether the subject reported ever having been a smoker.
Thompson JR, Sparrow JM, Gibson JM, Rosenthal AR. Cataract and Survival in an Elderly Nondiabetic Population. Arch Ophthalmol. 1993;111(5):675-679. doi:10.1001/archopht.1993.01090050109039