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June 1993

A Screening Test for Integrative Visual Dysfunction in Alzheimer's Disease

Author Affiliations

From the W. K. Kellogg Eye Center (Dr Trobe) and the Departments of Ophthalmology (Dr Trobe), Neurology (Dr Trobe), and Psychology (Dr Butter), University of Michigan, Ann Arbor.

Arch Ophthalmol. 1993;111(6):815-818. doi:10.1001/archopht.1993.01090060103031

• Objective.  —To develop a screening test to help ophthalmologists detect visually symptomatic patients with as yet undiagnosed Alzheimer's disease.

Design.  —Administration of a battery of tests consisting of items modified from existing psychometric materials to decrease examination time and increase ease of scoring.

Participants.  —Fourteen patients with Alzheimer's disease and prominent visual symptoms; 53 control subjects matched to the patients with Alzheimer's disease for age, sex, and educational level; and 22 patients with subnormal visual acuity or visual fields who did not have Alzheimer's disease.

Results.  —The novel battery of tests distinguished all 14 visually symptomatic patients with Alzheimer's disease from patients without Alzheimer's disease and control subjects.

Conclusion.  —This battery of tests should enhance the ophthalmologic detection of Alzheimer's disease.