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Article
June 1993

Multifocal FibrosclerosisReport of a Case of Bilateral Idiopathic Sclerosing Pseudotumor and Retroperitoneal Fibrosis

Author Affiliations

From the Division of Ophthalmology, Mt Sinai Medical Center, and the Department of Ophthalmology, School of Medicine, Case Western Reserve University, Cleveland, Ohio (Dr Levine); Department of Ophthalmology, Cleveland Clinic Foundation (Dr Kaye); Department of Pathology, Akron (Ohio) General Medical Center (Dr Mair); and College of Medicine, Northeastern Ohio Universities, Akron, and Akron City Hospital (Dr Bates).

Arch Ophthalmol. 1993;111(6):841-843. doi:10.1001/archopht.1993.01090060129037
Abstract

• We describe a 56-year-old white man who presented with gradual and progressive visual loss and subsequent hypertension and pedal edema. A computed tomographic scan of the orbits showed bilateral diffuse retrobulbar masses, and an abdominal computed tomographic scan showed a diffuse retroperitoneal mass invading the aorta, ureters, and inferior vena cava. Biopsies of the orbit and abdomen confirmed a heterogeneous cell population and marked fibrosis consistent with a sclerosing inflammatory process. Bilateral sclerosing orbital inflammatory disease should cue the physician to suspect coexisting systemic disease. This report is the fourth to document bilateral sclerosing orbital inflammatory disease and the second to have obtained biopsies of the orbit and abdomen showing histologic similarities.

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